BDBM373711 US10246444, Example 40

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CCSS1

InChI Key InChIKey=QCVAULIYZATFDX-UHFFFAOYSA-N

Data  13 IC50  21 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373711   

TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM373711(US10246444, Example 40)
Affinity DataKd: >1.00E+4nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent